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Gates, Wellcome bet $40M on Kymab’s antibody...

Cambridge, U.K.’s Kymab touts its drug development platform as an ideal way to spotlight new antibodies, and some bright minds would seem to agree, as the Wellcome Trust and Bill and Melinda Gates Foundation have teamed up on a $40 million round for the biotech. Under the Series B terms, each organization will hand over $20 million to support the company’s Kymouse technology, a genetically engineered mouse...

New Protein Finding Gives Hope to Infertility Pati...

Answering the question of “how do babies come in this world” is not easy at any age. You may laugh now, but as children we all heard the stories about some birds and some bees, some storks or other similar versions, while as adults, we are probably telling our children the same tales, so they can find out later, in an academical environment, the truth about conception and birth. But science went even further in trying to...

High protein levels linked to cell death in Parkin...

Researchers may have discovered how a genetic mechanism in a common cause of Parkinson’s works to destroy brain cells in patients–a finding that could help scientists develop new therapies for the devastating disease. Though most causes of Parkinson’s cases are unknown, mutations in a gene called leucine-rich repeat kinase 2–or LRRK2, pronounced “lark two” or “lurk...

Researchers replicate controversial stem cell-clon...

Scientists report that they have replicated a method of growing stem cells from adults using cloning techniques–a discovery that could help propel patient-specific regenerative therapies for a myriad of medical conditions and diseases. Using cells taken from two adult men, investigators from the Research Institute for Stem Cell Research of CHA Health Systems in Los Angeles and Advanced Cell Technology in Marlborough,...

Stabilizing protein complex in brain offers hope f...

A team of investigators has identified a new class of compounds that could work in a specific protein complex in the brain to provide a safe route toward reversing the devastating symptoms of Alzheimer’s. Known as the retromer protein complex, these proteins are found in reduced levels in the brains of Alzheimer’s patients. Retromers play a crucial role in neurons, steering amyloid precursor protein away from a...

The human ‘hairless’ gene identified

It’s not a hair-brained idea: A new research report appearing in the April 2014 issue of The FASEB Journal explains why people with a rare balding condition called “atrichia with papular lesions” lose their hair, and it identifies a strategy for reversing this hair loss. Specifically the report shows for the first time that the “human hairless gene” imparts an essential role in hair biology by...

Stroke drug shows promise for people with Lou Gehr...

Keck School of Medicine of USC neuroscientists have unlocked a piece of the puzzle in the fight against Lou Gehrig’s disease, a debilitating neurological disorder that robs people of their motor skills. Their findings appear in the online edition of the Proceedings of the National Academy of Sciences of the United States of America, the official scientific journal of the U.S. National Academy of Sciences. “We know...

Experimental drug could thwart measles outbreaks

A new antiviral drug may provide an effective way to treat measles in those who have not been vaccinated. When tested in an oral form in animals infected with a similar version of the measles virus, the experimental drug not only prevented animals from dying of the disease, but it significantly reduced virus levels. Developed by scientists from the Institute for Biomedical Sciences at Georgia State University, the Emory...

Good vibrations: Using light-heated water to deliv...

Researchers from the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, in collaboration with materials scientists, engineers and neurobiologists, have discovered a new mechanism for using light to activate drug-delivering nanoparticles and other targeted therapeutic substances inside the body. This discovery represents a major innovation, said Adah Almutairi, PhD, associate professor...

Nano-paper filter removes viruses

Nanotechnology and Functional Materials, Uppsala University have developed a paper filter, which can remove virus particles with the efficiency matching that of the best industrial virus filters. The paper filter consists of 100 percent high purity cellulose nanofibers, directly derived from nature. The research was carried out in collaboration with virologists from the Swedish University of Agricultural Sciences/Swedish...
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