High Throughput Screening
30th and 31st January, Millennium Gloucester Hotel, London Sponsored by: Caliper Life Sciences & Genedata Supported by: HTScreening.net, Combichem.net, Pharmafocus, Pharmafile, Inpharm.com & DrugResearcher.com

In recent years pharmaceutical R&D productivity has been experiencing decline despite increased research and development spending. Ten years ago high throughput screening was regarded as the potential saviour of drug discovery, but in reality HTS and uHTS have not lived up to their hype – why is this and what can still be achieved with the use of these assays?

SMi’s 4th Annual Conference, High Throughput Screening – The Application of HTS in current and Future Drug Discovery, will provide attendees with the latest insight into this important application, covering market dynamics, improved technologies and thoughts for the future. Further, the conference will address how HTS-based lead generation can be made to deliver, the benefits of this application and where the industry will be in the next 5 years. Additional key issues to be addressed by leading experts in the industry include, opportunities for in silico screening, the screening of protein-protein interactions and data analysis and mining.

Learn how to deal with critical bottlenecks and other issues reducing the efficiency of the drug discovery process through the use and application of better high throughput screening methods and tools.

A must attend event for those wishing to improve their drug discovery productivity!

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EARLY BIRD DISCOUNT AVAILABLE
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The early bird registration deadline is 31st October 2005. Please register before this date to receive a reduced rate.

To register simply go to: http://www.smi-online.co.uk/goto/htscreening.asp?emref=T14ES131063506

Discounts are also available for group bookings, contact James Holland on tel: +44 (0)20 7827 6180 or mailto:jholland@smi-online.co.uk
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A unique opportunity to learn from leading industry experts including:

- Dr Jonathan Mason, Executive Director, Medicinal Informatics, Structure & Design, Pfizer
- Dr Lorenz Mayr, Executive Director, BioChemical Assay Development & Screening, Novartis
- Dr Gregory Kaczorowski, Senior Director, Ion Channel Department, Merck
- Dr David Keeling, Director, Lead Generation Biology, Astrazeneca
- Dr Mary Jo Wildey, Senior Research Fellow; Screening & Compound Logistics Centre Team Lead, Johnson & Johnson
- Dr Alexander Hillisch, Director, Medicinal Chemistry & Head, Computational Chemistry, Bayer Healthcare
- Dr Stephen Clulow, Director, Lead Discovery, Cambridge Antibody Technology
- Dr Dominique Besson, HTS Services Group Leader, Serono

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Benefits of Attending:

- THE APPLICATION OF HTS IN DRUG DISCOVERY TODAY AND TOMORROW: What are the benefits of HTS-based drug discovery? Discover the future of HTS – how will HTS progress in the next 5 years? Learn how HTS-based lead generation can be made to deliver and it’s benefits in lead optimisation and CD delivery
- OPPORTUNITIES FOR IN SILICO SCREENING: Review the latest techniques – take a close look at ligand and target-based in silico screening
- SCREENING OF PROTEIN-PROTEIN INTERACTIONS: Learn how to interfere with protein-protein interactions, uncover the current challenges and limitations and hear success stories from the Lead Discovery Centre at Novartis
- HOW DOES HTS DELIVER VALUE IN DRUG DISCOVERY? Understand the link between HTS, chemoinformatics and lead generation
- DATA ANALYSIS AND MINING: Hear case examples from top pharmaceutical companies as they discuss preferred methodologies to deliver better leads in the drug discovery process
- INDUSTRY EXPERTS: Network with influential experts from leading pharmaceutical companies and learn from their experiences and expertise

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PLUS A HALF-DAY POST-CONFERENCE EXECUTIVE BRIEFING
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Cell-Based Screening
25th January 2006 (AM), Millennium Gloucester Hotel, London
In association with DiscoverX

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To register simply go to: http://www.smi-online.co.uk/goto/htscreening.asp?emref=T14ES131063506

Discounts are available for group bookings, contact James Holland on
tel: +44 (0)20 7827 6180 or mailto:jholland@smi-online.co.uk
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Sponsorship options:

SMi Group offers excellent opportunities to profile your company through tailored sponsorship packages. For details contact Adrian Johnston on tel: +44 (0)20 7827 6074 or mailto:ajohnston@smi-online.co.uk =======================================================================