Applied Biosystems Introduces New Power SYBR Green Reagents for Real-Time PCR
Power SYBR Sets a New Standard of Quality and Performance for Real-Time PCR Using SYBR Green Dye
FOSTER CITY, Calif. & SALT LAKE CITY–(BUSINESS WIRE)–Oct 26, 2005 - Applied Biosystems (NYSE:ABI), an Applera Corporation business, today announced the launch of Power SYBR(R) Green PCR Master Mix, a new line of reagents for real-time PCR gene expression applications.
SYBR(R) Green dye binds to any double stranded DNA molecule, offering a flexible and easy to use labeling method for real-time PCR.
“Power SYBR(R) Green PCR master mix is the next generation in SYBR-based real-time technology, providing researchers a cost effective and reliable chemistry with enhanced sensitivity for gene expression analysis, gene detection, and quantitation,” said Peter M. Dansky, Vice President and General Manager, PCR Consumables Business, Applied Biosystems. “This product introduction enhances our product portfolio for real-time PCR applications and is part of our larger strategy to grow our consumables business.”
Applied Biosystems Power SYBR(R) Green PCR Master Mix offers improved sensitivity through a newly optimized formulation. Power SYBR(R) Green PCR Master Mix minimizes variation and ensures consistent experimental results. Extensive validation studies were conducted to demonstrate enhanced sensitivity down to two copies per target.
“While TaqMan(R) chemistry is considered the gold standard platform for gene expression applications requiring high sensitivity and specificity, Applied Biosystems Power SYBR(R) Green reagents offer comparable sensitivity, but at lower cost, for researchers who opt to use SYBR(R) Green for specific applications, such as initial screening, target validation, or rapid assay development,” added Dansky.
Power SYBR(R) Green PCR Master Mix replaces the SYBR(R) Green PCR Master Mix in existing Applied Biosystems protocols using the same reaction preparation and thermal cycling conditions. Applied Biosystems offers a complete application solution for gene expression analysis, including an integrated suite of consumables and instruments, such as the Applied Biosystems Expression Array System, the Nucleic Acid PrepStation, TaqMan(R) Genomic Assays, TaqMan(R) Low Density Arrays, Real-Time PCR systems, primer and probe sets, reagents, disposables and software.
About Applera Corporation and Applied Biosystems
Applera Corporation consists of two operating groups. The Applied Biosystems Group serves the life science industry and research community by developing and marketing instrument-based systems, consumables, software, and services. Customers use these tools to analyze nucleic acids (DNA and RNA), small molecules, and proteins to make scientific discoveries and develop new pharmaceuticals. Applied Biosystems’ products also serve the needs of some markets outside of life science research, which we refer to as “applied markets,” such as the fields of: human identity testing (forensic and paternity testing); biosecurity, which refers to products needed in response to the threat of biological terrorism and other malicious, accidental, and natural biological dangers; and quality and safety testing, for example in food and the environment. Applied Biosystems is headquartered in Foster City, CA, and reported sales of nearly $1.8 billion during fiscal 2005. The Celera Genomics Group (NYSE:CRA) is engaged principally in the discovery and development of targeted therapeutics for cancer, autoimmune and inflammatory diseases. Celera Genomics is leveraging its proteomic, bioinformatic, and genomic capabilities to identify and validate drug targets, and to discover and develop small molecule therapeutics. It is also seeking to advance therapeutic antibody and selected small molecule drug programs in collaboration with global technology and market leaders. Celera Diagnostics, a 50/50 joint venture between Applied Biosystems and Celera Genomics, is focused on discovery, development, and commercialization of diagnostic products. Information about Applera Corporation, including reports and other information filed by the company with the Securities and Exchange Commission, is available at http://www.applera.com, or by telephoning 800-762-6923. Information about Applied Biosystems is available at http://www.appliedbiosystems.com/.
Applied Biosystems Forward-Looking Statements
Certain statements in this press release are forward-looking. These may be identified by the use of forward-looking words or phrases such as “should” among others. These forward-looking statements are based on Applera Corporation’s current expectations. The Private Securities Litigation Reform Act of 1995 provides a “safe harbor” for such forward-looking statements. In order to comply with the terms of the safe harbor, Applera Corporation notes that a variety of factors could cause actual results and experience to differ materially from the anticipated results or other expectations expressed in such forward-looking statements. These factors include but are not limited to (1) rapidly changing technology and dependence on the development and customer acceptance of new products; (2) sales dependent on customers’ capital spending policies and government-sponsored research; and (3) other factors that might be described from time to time in Applera Corporation’s filings with the Securities and Exchange Commission. All information in this press release is as of the date of the release, and Applera does not undertake any duty to update this information, including any forward-looking statements, unless required by law.
For Research Use Only. Not for use in diagnostic procedures.
NOTICE TO PURCHASER: LIMITED LICENSE
The PCR process, 5′ nuclease processes and dsDNA-binding dye processes are covered by patents owned by Roche and by patents owned by or licensed to Applera Corporation. Purchase of Power SYBR(R) Green PCR Master Mix is accompanied by a limited license to use it with detection by a dsDNA-binding dye as described in U.S. Patents Nos. 5,994,056 and 6,171,785 and corresponding patent claims outside the United States for the purchaser’s own internal research. No real-time apparatus or system patent rights or any other patent rights, and no right to use this product for any other purpose are conveyed expressly, by implication or by estoppel. This product is for research purposes only. Diagnostic uses require a separate license from Roche. Further information on purchasing licenses may be obtained by contacting the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.
The SYBR(R) Green dye is sold pursuant to a limited license from Molecular Probes, Inc. under U.S. Patent No. 5,436,134 and 5,658,751 and corresponding foreign patents and patent applications.
Applied Biosystems is a registered trademark and Applera is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries. TaqMan is a registered trademark of Roche Molecular Systems, Inc. SYBR is a registered trademark of Molecular Probes, Inc. Copyright(C) 2005. Applied Biosystems. All rights reserved.
Contact Applied Biosystems Sophie Patel, 650-554-2732 (Media) sophia.patel@appliedbiosystems.com Ana Kapor, 650-638-6227 (Investors) kapora1@appliedbiosystems.com
