Bio Screening Industry News

Archive for December, 2005

December 30, 2005

BellBrook Labs finds its biotech niche

Filed under: North America, HT Screening — admin @ 7:59 pm

By Laurel Norris and Christine Lepple MADISON — Most scientists believe new technology will sell itself to consumers.

But the founders of BellBrook Laboratories, located in the heart of Madison’s University Research Park, knew they had to market the science before others would buy into it.

“A lot of biotechnology companies start with the technology. Our company is market driven from the start by finding the technology to that market need,” said Bob Lowery, BellBrook Labs president and co-founder.

“For me, it was about understanding the market well and seeing opportunities for unmet needs … we formed BellBrook to address those needs.”

The need BellBrook Labs identified was for high-volume screening of possible drug targets. The idea was to speed up the process drug companies use to determine where to focus their research, saving them time and money.

“On the discovery end, which is where we are, very few of the compounds that come out of discovery actually make it into clinical trials,” Lowery said. “It’s all very high risk.”

BellBrook Labs was founded in August 2002 to take advantage of the rapidly growing need for high throughput screening assays in drug discovery laboratories. Leveraging contacts within the biotech community are strengths of BellBrook’s success, which had led to $200,000 in revenues by 2004.

“One of the most important decisions I made early on in starting the company was getting someone to join me who could focus on the business, other than the science,” Lowery said.

That “someone” turned out to be John Majer, now BellBrook Labs’ Chief Operating Officer. Lowery and Majer worked together at Promega, a leading life sciences firm in Madison.

The BellBrook Team now consists of 11 employees who have been hired from local firms or through Lowery’s past contacts.

“There’s a lot of personal acquaintances as well as people we’ve brought into the company they have all been involved in drug discovery,” he said.

When it came to looking for investors to finance the business, Lowery stayed close to home. Half of the people contributing to BellBrooks start-up capital of $1.5 million were from Wisconsin, while the other half came from Lowery’s contacts in his home state of California.

“I had never done a private equity financing,” he said. “It was a challenge getting my arms around the whole thing, what it entailed, the process, best way to do it.”

In addition, Lowery used angel investors and resource programs to help in starting up the small biotech firm.

“The angel groups help you hone your business plan and documents you’re providing to your potential investors,” he said.

One of the most valuable lessons Lowery learned was realizing that he would have to do financing.

“I planned to finance the company completely with grants, which was impossible,” he said. “We were going to have to go out there and ask people for money.”

Recently, the small biotech firm took its second product to the market. With much anticipation, Lowery believes within five years BellBrook Labs will near $15 million in revenues. For a small biotech firm in Madison, finding the right market niche will be the key to long-term success.

Norris and Lepple are students in the UW-Madison Department of Life Sciences Communications. They are part of a instructional project led by Wisconsin Technology Council President Tom Still.

Source: WIS Business

December 20, 2005

Screening Europe: Call for Poster Presentations

Filed under: Europe — admin @ 2:30 pm

If you would like to submit a proposal for a poster presentation at this meeting, please submit online NOW!
Available poster space is limited!
Deadline: 9th January 2006

In 2006 the conference will be held in parallel with MedChem Europe allowing delegates to network with colleagues from this closely allied field.

Did you know you can save your company $US 200 by registering before Friday 23rd December (just $US 399 for academics)?
As a personal thank you, anyone who registers by then will also receive a $US 50 voucher which can be redeemed on Amazon.com. Handy for that last minute Christmas present!

December 19, 2005

Joint Meeting of The German Physiologic Society and The European Federation of Physiologic Societies 2006 in Munich, March 26 - 29, 2006

Filed under: Europe — admin @ 2:21 pm

Satellite Symposium by Nanion Technologies at the upcoming Annual Meeting of the German Physiological Society in Munich (26.- 29.3.2006), Nanion will organize a satellite symposium on ‘New and Emerging Techniques in Electrophysiology’. Prof. Fred Sigworth will give the plenary lecture for the symposium. The symposium will be on Saturday, the 25th of March and will start at 10:00 am. The announcement with tentative list of speakers is available as PDF ( http://nanion.de/pdf/Satellite.pdf).
If you plan to attend, please briefly send an email with subject ’symposium’ to info@nanion.de

December 16, 2005

Honeycomb Connect Convention Don CeSar Beach Resort in St. Pete Beach, Florida January 29th - 31st, 2006

Filed under: North America, USA and Canada, Business and Investment — admin @ 2:41 pm

Over the last 12 months a select group of your peers have been enjoying the benefits associated with membership to the most cutting edge and high value, executive communities in existence today. Join us on January 29th - 31st at the Don CeSar Beach Resort in St. Pete Beach, Florida for our annual People In Life Sciences (P.I.L.S.) members meeting.

Take part in in-depth discussions and hear from industry leaders as they discuss:

Pharmaceutical Operational Excellence
Eileen Morrissey, Vice President, Global Operational Excellence
MERCK

Drug Delivery Challenges Roundtable Discussion led by
Mak Jawadekar, Associate Research Felloww, Director
Honeycomb Connect Member
PFIZER

The Pfizer Approach to M&A
Gareth Creasey, Director, Acquisitions, Collaboration and Divestures, Honeycomb Connect Member
PFIZER INFORMATICS

Fraud and Abuse Issues
Daniel Garen, Sr. Counsel
BAYER HEALTHCARE

Compliance Maintenance, Roundtable Discussion led by
Jeff Hartry, Director of Quality Assurance, Honeycomb Connect Member
CANGENE CORPORATION

Team Building
Jack McGuire, Exec. Vice President, Biomedical Services
AMERICAN RED CROSS

Employee Development and Retention, Round Table Discussion led by
Karen Walker, Director, QC
ABGENIX

Risk-Based Compliance Decisions, Roundtable Discussion led by
Gerard J. Lohan, Senior Director, Worldwide GMP Quality
MERCK

among others…

Also receive a membership discount voucher worth $1,000 towards the 2006 Executive Membership Program. Register yourself before January 13th and bring along two additional colleagues at no cost.

For more information download the printable PDF of the event or email George Edwards at ged@honeycombworldwide.com or call 416.977.6555 x 237.

HURRY AND REGISTER BEFORE DATE SEATS ARE LIMITED!
You cannot afford to miss networking with the Pharmaceutical industries leaders.

**********************************************************************************************************************************************

People In Life Sciences (P.I.L.S)
The Honeycomb Connect People In Life Sciences (P.I.L.S) membership is made up of

100% of the Top 10* Pharma Companies, 92% of the Top 25* and 80% of the Top 50*.
*Based on Pharmaceutical Executive

Take a Look at Just Some of the Honeycomb Connect Members

Amgen
Aventis
Biogen idec
Boehringer Ingelheim
Eli Lilly and Company
Genzyme Corporation
Takeda Pharmaceuticals
Hoffman-La Roche Inc.
Johnson & Johnson
Merck & Company
GlaxoSmithKline
Novartis
Pfizer

As a key figure within your organization you are cordially invited to take advantage of our VIP Preview Package and join existing Honeycomb Connect members at the convention.
By doing so you will enjoy:

The opportunity to network with Honeycomb Connect members.
Full participation in the conference program and member-led roundtables.
Access to all formal and informal networking functions including meals, receptions and organized entertainment.
The ability to invite colleagues as part of our in-tandem program.
Privileged member accommodation rates at the resort.
The opportunity to help forge the 2006 member web-meeting agenda.

**********************************************************************************************************************************************

>> Interested in becoming a member?
http://www.honeycombconnect.com/home/page_56.ashx

>> Download the event pdf for more info Mention VIP code PEX-01 when registering and save %15

Honeycomb Connect , Part of The Honeycomb Worldwide Group of Companies, Suite 1515, 123 Edward Street, Toronto M5G 1E2

December 15, 2005

Microplate Instrument Trends

Filed under: Europe, Equipment, Reports — admin @ 2:41 pm

This market report summarizes the results of a comprehensive global Pharma/Biotech web-based survey on microplate instrumentation trends carried out in May 2005. The main survey looked at the factors that currently limit productivity from a microplate instrumentation perspective; current and future use of microplate detection instruments and microplate readouts; liquid handling for bulk reagent dispensing and sample addition; difficulty in enabling liquid handling applications and reliability of dispensing; current and future use of microplate washers and washing applications; comparative vendor use and respondent ratings; use of different microplate formats and total assay volumes; data point metrics; and microplate instrument budgets and breakdown.

Purchase report >>

XIXth International Symposium on Medicinal Chemistry

Filed under: Europe — admin @ 2:24 pm

Istanbul, Turkey - August 29 - September 2, 2006
The ISMC-2006 Symposium will be organized by the Turkish Association of Pharmaceutical and Medicinal Chemistry under the auspices of the European Federation for Medicinal Chemistry (EFMC).

This symposium is recognized worldwide as one of the leading Medicinal Chemistry meetings, as proven by its large international attendance, which varies between 1200 and 1500 participants from all over Europe, but also from the United States and Asia.

The Symposium will focus on important new scientific and technological developments in the drug discovery process; particularly those relevant to medicinal chemistry. The meeting will create an environment for in-depth, informed discussions highlighting the importance of medicinal chemistry in the pharmaceutical industry, academia and drug research. It will also provide opportunities to re-emphasise the crucial position of medicinal chemistry in the drug discovery process and its pivotal role in linking and exploiting the associated biological sciences. Therefore, the ISMC-2006 intends to create a forum for all scientists interested in medicinal chemistry and related fields.

More details regarding the participation and the scientific program are available via the symposium website: www.ismc2006.org

December 8, 2005

KineMed Presents Innovative New Assays for Measurement of in vivo Cartilage Dynamics at the World Congress on Osteoarthritis

Filed under: North America, Press Releases, HT Screening, Medicinal Chemistry — admin @ 5:15 pm

EMERYVILLE, Calif., Dec. 8, 2005 /PRNewswire/ — KineMed, Inc., a platform-based indications discovery and development drug company, announced today that two posters detailing results from a new product program will be presented at the World Congress on Osteoarthritis meeting to be held in Boston, MA from December 08, 2005-11th, 2005.

The presentation information is as follows:

Date: Friday, December 9th, 2005
Time: 1:30-3:00 pm, Eastern Standard Time
Location: Marriott Copley Place, Poster Session I
Titles of Presentations:
“SIMULTANEOUS MEASUREMENT OF CELL AND MATRIX
TURNOVER IN EXPERIMENTAL MODELS OF CARTILAGE
DEGENERATION” (Poster # P63).

“SYNOVIAL FLUID HYALURONAN: A POTENTIAL KINETIC
BIOMARKER OF EARLY OSTEOARTHRITIS” (Poster # P61).

KineMed KineMarker(TM) Product Programs in Osteoarthritis

KineMed’s proprietary in vivo KineMarker(TM) assays provide new, sensitive and high-throughput measures of several key pathways involved in the pathogenesis and treatment of degenerative joint conditions. These assays can be used in clinical as well as pre-clinical settings.

KineMed’s Cartilage Matrix KineMarkers(TM) are much more sensitive, reproducible and high-throughput than traditional methods, such as histological staining.

About KineMed, Inc.

KineMed, Inc. provides a proprietary set of tools for measuring the dynamics of molecular and cellular response to drugs in the intact organism, both in animals and humans. KineMed’s technology is ideally suited to enable the discovery of entirely new, unanticipated uses for compounds (an approach called repurposing or repositioning) by screening for activity in vivo across a wide variety of disease states. The breadth of therapeutic targets covered by KineMarker(TM) assays allows high-throughput screening in conditions beyond those typically evaluated. KineMed’s technology expedites the drug development process and provides real-time insight into conditions including metabolic disorders, cancer, and diseases of inflammation and neurodegeneration.

For further information about KineMed, please visit: http://www.kinemed.com

CONTACT: Lisa Misell, Ph.D., Vice President of Business Development ofKineMed, +1-510-655-6525, ext. 117, or Media: Justin Jackson, BurnsMcClellan, +1-212-213-0006, , for KineMed, Inc. jjackson@burnsmc.com

Web site: http://www.kinemed.com/

Maxim Pharmaceuticals Receives Recommendation from ISS in Favor of Proposed Merger with EpiCept Corporation

Maxim Pharmaceuticals, Inc. (NASDAQ:MAXM)(SSE:MAXM)announced today that the Institutional Shareholder Services, or ISS,has recommended that Maxim’s stockholders vote in favor of theproposal to approve and adopt the merger agreement and the merger withEpiCept Corporation. ISS is a leading provider of proxy voting andcorporate governance services to institutional investors, analyzingproxies and issuing informed research and objective voterecommendations for more than 33,000 companies across 115 marketsworldwide.

The Company urges stockholders who have not already done so tovote their shares. Stockholders who have questions or need moreinformation about the special meeting to be held on December 21, 2005,should contact the Company’s proxy solicitor, MacKenzie Partners, asshown below.

EpiCept has filed a registration statement that contains adefinitive proxy statement/prospectus with the Securities and ExchangeCommission. STOCKHOLDERS OF MAXIM AND OTHER INVESTORS ARE URGED TOREAD THE PROXY STATEMENT/PROSPECTUS (INCLUDING ANY AMENDMENTS ORSUPPLEMENTS TO THE PROXY STATEMENT/PROSPECTUS) REGARDING THE PROPOSEDMERGER BECAUSE IT CONTAINS IMPORTANT INFORMATION ABOUT EPICEPT, MAXIMAND THE PROPOSED MERGER. Maxim’s stockholders may also obtain a freecopy of the definitive proxy statement/prospectus, as well as otherfilings containing information about Maxim and EpiCept, withoutcharge, at the SEC’s Internet site (http://www.sec.gov). Copies of theproxy statement/prospectus and Maxim’s other filings with the SEC canalso be obtained, without charge, by directing a request to MaximPharmaceuticals, 8899 University Center Lane, Suite 400, San Diego, CA92122, Attention: Investor Relations, Telephone: 858-453-4040 orMacKenzie Partners, Inc. toll free at 800-322-2885, or direct at212-929-5500. If you are located in Sweden, you can call direct at+46-8-775-02-18.
PLEASE VOTE TODAY
If you have any questions or need assistance in voting your
proxy card, please contact our proxy solicitor
MacKenzie Partners, Inc.

In North America:
Call Toll Free - 800-322-2885 or call direct - 212-929-5500.

In Sweden:
Call WM DATA direct +46-8-775-02-18

Stockholders in Sweden may also fax their proxy cards to
WM DATA +46-8-775-01-95.

Swedish Shareholders may also vote through the Internet by
logging on to www.maxim.com/sgm

You will find your password included on your proxy card
recently mailed to you.

In Europe:
Call direct +44-(0)-207-170-4155

Maxim Overview

Maxim is a biopharmaceutical company dedicated to developinginnovative cancer therapeutics. Maxim has completed one Phase 3clinical trial of Ceplene(TM) plus Interleukin-2 combination therapyas a remission maintenance therapy for patients with acute myeloidleukemia. Maxim is also engaged in the discovery and development ofsmall-molecule apoptosis inducers and inhibitors to treat a wide rangeof disorders, including cancers and degenerative diseases. Using itsproprietary high-throughput screening technology and its chemicalgenetics approach several lead compounds have been identified. Currentefforts continue toward the development of these compounds eitherinternally or through strategic collaborative arrangements.

Ceplene and the apoptosis compounds are investigational drugs andhave not been approved by the U.S. Food and Drug Administration or anyinternational regulatory agency.

This news release contains certain forward-looking statements thatinvolve risks and uncertainties that could cause actual results to bematerially different from historical results or from any futureresults expressed or implied by such forward-looking statements. Suchforward-looking statements include statements regarding the proposedtransaction with EpiCept, the efficacy, safety and intendedutilization of Ceplene, the oral histamine formulation, and theapoptosis inducers, and the conduct and results of future clinicaltrials, and plans regarding regulatory filings, future research andclinical trials and plans regarding partnering activities. Suchstatements are only predictions and the Company’s actual results maydiffer materially from those anticipated in these forward-lookingstatements. Factors that may cause actual results to differ materiallyinclude the risk that Maxim and EpiCept may not be able to completethe proposed transaction, the risk that products that appearedpromising in early research and clinical trials do not demonstratesafety or efficacy in larger-scale or later clinical trials, the riskthat the Company will not obtain approval to market its products, andthe risks associated with the Company’s reliance on outside financingto meet its capital requirements and the risks associated withreliance on collaborative partners for further clinical trials,development and commercialization of product candidates. These factorsand others are more fully discussed in the Company’s periodic reportsand other filings with the Securities and Exchange Commission.

Note: The Maxim logo is a trademark of Maxim.

Editor’s Note: This release is also available on the Internet athttp://www.maxim.com

Humanetics and the Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Sign Exclusive License for Oral Agent to Protect and Strengthen the Immune System Against Radiation Exposure in Terrorist Attack

MINNEAPOLIS–(BUSINESS WIRE)–Dec 8, 2005 - Humanetics Corporation today announced the signing of a worldwide exclusive licensing agreement with The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., (HJF) to further develop an oral agent, BIO300, for strengthening and protecting the immune system against radiation exposure.

BIO300 was jointly developed by researchers at the Armed Forces Radiobiology Research Institute (AFRRI) and the National Institutes of Health (NIH). AFRRI, in Bethesda, Maryland, is part of the Uniformed Services University of the Health Sciences (USU), a Congressionally-chartered, fully-accredited, graduate education university operated by the Department of Defense. HJF, in Rockville, Maryland, is a private, not-for-profit organization chartered by Congress to support medical education and research at USU and throughout the military medical community.

BIO300 has been shown in animal models to be highly effective in protecting the immune system against harm caused by exposure to whole-body ionizing radiation. Under the exclusive license, Humanetics will assume responsibility for continued testing, development and commercialization of BIO300. A Cooperative Research and Development Agreement (CRADA), has been entered into with USU and HJF for Humanetics to collaborate with AFRRI, the nation’s premier center for radiation injury countermeasure research, and with the F. Edward Hebert School of Medicine, to test and develop BIO300. Humanetics intends to develop and commercialize BIO300 as an oral countermeasure to support and protect the immune system against challenges from exposure to ionizing radiation resulting from a terrorist attack or nuclear accident.

Humanetics and AFRRI are pursuing a number of target compounds, all of which have been shown to be effective in increasing survival in mice receiving otherwise lethal doses of radiation. Based on animal screening models, BIO300 has emerged as the leading candidate for commercialization.

Humanetics believes that as a result of the level of chaos likely following a catastrophic event such as a radiation accident or nuclear terrorist attack, civilians may have to rely solely on products in their possession before such a catastrophe. There are an estimated 90 million civilians in the 10 metropolitan areas considered at greatest risk from a terrorist attack. By developing oral countermeasures, Humanetics is pursuing the ability to provide products that may be distributed in advance of an event and will offer a level of protection presently unavailable to the American public.

“We are proud to have licensed this important oral agent developed at USU/AFRRI and the NIH, and look forward to further development in collaboration with AFRRI leading to final testing and commercialization of BIO300,” says Ronald Zenk, President and CEO of Humanetics. “Their discoveries provide a substantial platform from which we intend to develop a safe and effective oral countermeasure in the event of a radiation accident or radiological/nuclear terrorist attack.”

About Humanetics Corporation

Humanetics is a privately-held specialty pharmaceutical company headquartered in Minneapolis, Minnesota. The Company is focused on the rapid discovery, development and commercialization of orally-administered bioactive compounds for prevention and treatment of diseases in categories with urgent and unmet needs. The Company has several proprietary compounds in preclinical and/or clinical stages of development in the areas of bioterrorism, Alzheimer’s disease and obesity. For more information, visit: http://www.humaneticscorp.com.

This Press Release contains discussion of certain expectations regarding Humanetics’ future performance. These forward-looking statements are based on the Company’s current views and assumptions. Actual results could differ materially from these current expectations and projections, and from historical performance.

Contact For Humanetics Corporation Pam Pettinella, 952-404-1853 pam@latitude-c.com

BioFine 2006 May 4-5 Barcelona

Filed under: Europe — admin @ 2:33 pm

The BioFine exhibiton provides an ideal platform for companies offering outsourcing services in drug discovery, bioprocessing/biomanufacture and pharma chemicals as well as lab automation equioment.

In 2005 nearly 800 attendees were present at the event and for the 3rd BioFine event in May 2006 we are expecting an increase on this attendee level.
Why Barcelona?
6 of the top 10 pharmaceutical companies in the world have operations in Catalonia.
Now boosted by the attraction of investment in the region by major biotech companies.
Catalonia region now accounts for more than 21% of total R&D expenses in Spain.
Catalonia region accounts for 60% of all Spanish pharmaceutical production
Catalonia region has 50% of all Spanish pharmaceutical companies.
Where in Barcelona?

Palau De Congressos (situated adjacent to Barcelona’s key science parks.)

When in Barcelona?

Thursday May 04 & Friday May 05, 2006 (why not extend your stay to include the weekend and catch the Barcelona Grand Prix?)

For more details or to book your exhibiton stand please contact Jaymin on jaymin@sp2.uk.com or tel: +44 (0)1403 220754

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