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Mushroom-derived compound could stamp out HPV infection

A compound derived from mushrooms may provide a new therapeutic option for treating human papillomavirus and curbing HPV-related cancers.

Researchers at the University of Texas Health Science Center Medical School at Houston treated HPV-positive mice with active hexose correlated compound, or AHCC, a natural supplement produced from the shiitake mushroom family, and found that a once-daily treatment of the compound began to rid the mice of HPV after 30 days.

The study results point to an AHCC-based compound as a possible approach to eliminating HPV, which infects up to 70% of sexually active adults at some point in their lives. HPV DNA has been detected in 99.7% of cervical cancer biopsies–the largest known causative relationship of any cancer. Several other types of cancer are also HPV-related, including anal cancer, oropharyngeal cancer, vaginal cancer, vulvar cancer and penile cancer.