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11th EFMC Short Course on Medicinal Chemistry Engineering of Biopharmaceuticals Oegstgeest (near Leiden), The Netherlands – September 27-30, 2015

This intensive course is intended for scientists with interests in the field of peptide and protein engineering covering topics around synthetic peptides, engineered proteins and therapeutic antibodies.

The number of participants will be limited to 35 to assure the possibility for in-depth discussions. The presentations and tutorials will be given by academic and industrial experts and will cover broad historical perspectives and in depth details of important engineering technologies. The presenters will also include interesting applications as well as future aspects in an informal approach aiming for high level of interaction of the participants.

Course outline

The development of future biopharmaceuticals will depend on research at the interfaces between several scientific disciplines including organic chemistry, physical chemistry, biophysics, protein chemistry and molecular biology. The interplay between these fields will have a key role for improving our molecular understanding of peptides and proteins and thus for developing future drug candidates. This course will focus on strategies on how to design and engineer biopharmaceuticals and will provide participants with insight to this important field of bioscience, which are applicable in academic and pharmaceutical contexts. The course will cover several fundamental aspects of peptide chemistry methodologies, selective modifications of proteins, ligation chemistries and regioselective coupling reactions. The biophysical characterization of peptide and proteins will be integrated in the lectures. The course will also cover various methods of semi-synthetic and synthetic modifications of proteins with focus on the application to drug discovery. Finally the course will give an insight to therapeutic antibodiesincluding screening, optimization an engineering aspects.

Thus, various issues of development of biopharmaceuticals as well as discussions of different strategies to improve peptide and protein properties to biopharmaceuticals will be the primary focus of the course.

Register before the deadline of June 22!

Interested participants are asked to pre-register for the course. A final registration confirmation will be sent after the pre-registration deadline of June 22. In case of an insufficient number of participants, EFMC reserves the right to cancel the course.

Comments of previous EFMC Short Course Participants

  • “Very nice set-up. Limited number of participants. Excellent opportunity to speak to peers about medchem issues and others.”
  • “The availability of the speakers during the sessions and exercises was a plus. The tutors were very experienced, motivated and motivating, and very good in communication.”
  • “Having the whole meeting ‘under one roof’ is appreciated. The castle is a very nice and comfortable location to organise an event such as the Short Course.”
  • “The speakers of the Engineering of Biopharmaceuticals Course (Spring 2014) were of high quality and well prepared.”

Course Organiser
Jesper LAU (Novo Nordisk, Denmark)

Local Organiser
Henk TIMMERMAN (VU University Amsterdam, The Netherlands)

Registration fee
€1.675 – including accommodation, breakfast, coffee breaks, lunches and dinners during the 3 days of the course.

 

More information on registration can be found on www.efmcshortcourses.org