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Self-assembling cages built from DNA

Move over, nanotechnologists, and make room for the biggest of the small. Scientists at the Harvard’s Wyss Institute have built a set of self-assembling DNA cages one-tenth as wide as a bacterium. The structures are some of the largest and most complex structures ever constructed solely from DNA, they report online in Science. Moreover, the scientists visualized them using a DNA-based super-resolution microscopy method...

Honey fights antibiotic resistance

Honey, that delectable condiment for breads and fruits, could be one sweet solution to the serious, ever-growing problem of bacterial resistance to antibiotics, researchers said. Medical professionals sometimes use honey successfully as a topical dressing, but it could play a larger role in fighting infections, the researchers predicted. “The unique property of honey lies in its ability to fight infection on multiple...

Experimental supplement extends lifespan, stops me...

A drug supplement that activates a protein involved in metabolic balance showed an extension in lifespan and improvement in the overall health of mice, according to a new study.The findings, published Feb. 27 in Cell Reports, may eventually help scientists develop therapies to minimize the effects of age-related metabolic and chronic diseases on the human body. Researchers, led by Dr. Rafael de Cabo of the National Institute...

HIV immune discovery

A new discovery that explains how the body’s immune system makes a potent antibody that blocks HIV infection may be an important step toward developing a vaccine against the virus. Scientists from the National Institute of Allergy and Infectious Diseases analyzed data from the results of a clinical trial of the only experimental HIV vaccine to date that’s shown modest success in people. Trial results showed that...

University of Notre Dame team IDs new class of ant...

Researchers from the University of Notre Dame may have discovered a new class of antibiotics to combat deadly bacteria like methicillin-resistant Staphylococcus aureus, or MRSA, which pose serious threats to public health. Led by Mayland Chang and Shahriar Mobashery, investigators identified the new class of antibiotics, called oxadiazoles, by using virtual screening to sift through 1.2 million compounds. Researchers found...

Gel steers tooth tissue formation

A bit of pressure from a new shrinking, sponge-like gel is all it takes to turn transplanted unspecialized cells into cells that lay down minerals and begin to form teeth. The bioinspired gel material could one day help repair or replace damaged organs, such as teeth and bone, and possibly other organs as well, scientists from the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard School of...
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