nav-left cat-right
cat-right

New Pig Models for Cancer Studies

A naturally occurring line of immunodeficient pigs can support the growth of human tumors injected under their skin, offering a promising new large-animal model for studying human cancers and testing new drugs and treatment strategies. The ability of human melanoma cells and pancreatic carcinoma cells to grow in these pig models is described in an article in BioResearch Open Access, a new bimonthly peer-reviewed open...

OGT Awarded $3.6M for Next-Generation Sequencing

Oxford Gene Technology (OGT) next-generation sequencing service team has been awarded two EU-funded clinical research grants worth €3 million (approximately $3.6 million). OGT will be providing genomic analysis and commercialization services for two international studies, EUCLIDS and PATHSEEK. EUCLIDS (EU Life-threatening Infectious Disease Study), is a five-year, large-scale study to identify genomic variants that...

TAP, Open University to Develop 3-D CNS Tissue Mod...

TAP Biosystems and the U.K.’s Open University (OU) established a partnership to develop 3-D human central nervous system (CNS) tissue models based on TAP’s collagen RAFT technology for drug discovery and preclinical drug testing. The aim is to manufacture gel-based neural tissue models using glial cells and neurons that can be used for research and for applications including preclinical screening of drug...

Eleven Increases Series A Fundraising to $45M for ...

Eleven Biotherapeutics secured $20 million from new and existing investors in an extension to its Series A financing, which takes the total raised to $45 million. JAFCO joined the fundraising round as new investor together with financial input from existing investors Third Rock Ventures and Flagship Ventures. Eleven Bio will use the funds to progress its initial protein therapeutic candidate EBI-005 into clinical...

Toxins found in traditional Chinese medicine

A host of potential toxins, allergens and traces of endangered animals showed up in DNA sequencing tests on 15 Chinese traditional medicines, researchers said on Thursday. Such therapies have been used in China for more than 3,000 years, but have risen in popularity outside Asia in recent decades and now amount to a global industry worth hundreds of millions of dollars a year, according to the study in PLoS Genetics. Despite...

Development of a Label-free Assay for Sodium-Depen...

Soo-Hang Wong Alice Gao Sabrina Ward Charles Henley Paul H. Lee paull@amgen.com Abstract The most widely used assay format for characterizing plasma membrane transporter activity measures accumulation of radiolabeled substrates in tissues or cells expressing the transporters. This assay format had limitations and disadvantages; therefore, there was an unmet need for development of a homogeneous,...
Page 3 of 1612345...10...Last »