Archive for the ‘BioInformatics’ Category

Odense & Aarhus, Denmark — December 18, 2007 — ACE BioSciences, an emerging pharmaceutical company focused on developing novel protein-based vaccines and antibodies to address infectious diseases, and CLC bio, the world’s leading bioinformatics solutions provider, today announced a collaborative bioinformatics agreement.

Dr. Ingelise Saunders, Chief Executive Officer at ACE BioSciences said,
‘At ACE BioSciences we place considerable emphasis on selecting partners based on their scientific know-how – and in that regard we recognize CLC bio as the leading company within bioinformatics, with a global reputation and internationally renowned experts. We see this collaboration as a significant opportunity to augment and expand our bioinformatics platform to increase efficiency, enhance our analyses, and accelerate our research.’

Dr. Jannick D. Bendtsen, project manager and Senior Scientific Officer at CLC bio commented,
‘We are looking forward to this collaboration, which is scientifically interesting and challenging. The implementation of our customized software will streamline and fast-track analysis and further increase statistical confidence in the selection of novel candidates for inclusion in the ACE BioSciences’ development portfolio. Implementation of automated target validation protocols will increase efficiency and the rate of data throughput, improve quality assurance and enhance data security.’

Under the terms of the agreement, CLC bio will upgrade and expand ACE BioSciences’ existing bioinformatics platform to ensure the company is taking advantage of the most up-to-date, relevant, and innovative software, including state-of-the-art protein vaccine target characterization. In addition, CLC bio will provide greater integration and cross-referencing capabilities, securing for ACE BioSciences the ability to apply more extensive statistical analyses to its databases and laboratory information. CLC bio’s customized solution will strengthen ACE BioSciences’ ability to compare, rank, and prioritize potential vaccine targets.

The solution provided to ACE BioSciences consists of a number of CLC workbenches for DNA, RNA, and protein sequence analysis, supplemented with customized bioinformatics modules that are proprietary for ACE BioSciences

Read more about CLC bio’s customized software solutions on:
www.clcbioconsulting.com

About ACE BioSciences

ACE BioSciences is an emerging pharmaceutical company focused on developing novel protein-based vaccines and antibodies to address infectious diseases. It has unique expertise in the extraction and analysis of the cell surface proteins used by pathogens (eg bacteria, viruses and fungi) to interact with and infect human host cells.

The company’s lead product, ACE393, is an injectable vaccine that is on track to become the world’s first commercial vaccine for Travellers’ Diarrhoea caused by Campylobacter infection, having successfully completed Phase I clinical trials in March 2007.

Campylobacter is one of the greatest causes of gastroenteritis in the developed world as well as a significant contributor to travellers’ diarrhoea. The annual global commercial market for a Campylobacter vaccine is estimated to be worth € 350 million.

ACE BioSciences aims to develop a portfolio of products independently and in collaboration with other companies and as part of that strategy the company signed a collaborative development agreement with the US Naval Medical Research Center (NMRC) to progress ACE393 through Phase II clinical trials. In addition to ACE393, the company is working on ACE537, an oral, Phase I, Enterotoxigenic E Coli (ETEC) vaccine which has the potential to be the first to market in the US and EU and which combats the single biggest cause of travelers diarrhoea. It is also working on a vaccine for Streptococcus pneumoniae, the bacterium responsible for Pneumococcal disease.The market for a Streptococcus product would be multibillion and ACE BioSciences aims to partner the project.

About CLC bio

CLC bio is the world’s leading full-service bioinformatics solution provider, solely focusing on the development of bioinformatics: software, hardware, data analysis, and custom-designed bioinformatics algorithms. CLC bio is an Apple solution provider and value added reseller.

CLC bio’s mission is to be among the most innovative bioinformatics companies in the 21st century. This is realized through:

• Development of bioinformatics software and hardware based on the latest scientific findings
• User-friendly, integrated and intuitive cross-platform software solutions
• Continuous focus on customer needs and superior customer service
• Frequent product updates including the latest IT technologies and bioinformatics algorithms
• A flexible IT architecture, enabling customers to buy or develop individualized solutions at a reasonable price

Aarhus, Denmark — November 29th, 2007 — CLC bio, the world’s leading bioinformatics solution provider, today announced the release of CLC Bioinformatics Database. This powerful and versatile database solution enables research organizations, from small university departments and clinical labs to large biotech and pharmaceutical companies, to maximize their potential, through increased productivity. An increase in productivity will help increase the number of drug candidates, by empowering scientists to do more with their research. In turn this gives companies a more efficient use of R&D budgets.

Dr. Darrol Baker, Sales Manager at CLC bio states,
CLC Bioinformatics Database raises the bar for what can be expected from a database solution! Our development team has focused on eliminating classic obstacles such as different operating systems, limited support for database formats, or limited access to a central storage facility. The security and management facilities in CLC bio’s Bioinformatics Database can potentially help organizations stop misuse or loss of data, as well as help protect their intellectual property rights.

For organizations already having an existing relational database in use for sharing DNA, RNA, and protein sequence data, the CLC Bioinformatics Database interface can be customized to store and retrieve data directly from that database. The result is a solution that enables all users of CLC bio’s software to work directly on – and fully integrated with – the organization’s existing database. This ensures the same data sharing, data searching and data security characteristics as if the database had been a stand alone database – except for the fact that the CLC bio data is now fully integrated with all other sequence data in the organization. The design, API-customization, implementation, and data migration can be carried out by the customer or by CLC bio’s consultants.

As with all other of CLC bio’s solutions, CLC Bioinformatics Database is cross-platform, running on Mac OS X, Windows, and Linux. Additionally, this solution will enable users across various workgroups to work on data in a central, shared, and secure relational database. CLC Bioinformatics Database integrates and runs smoothly with several types of databases, including Oracle, PostgreSQL, and MySQL.

For more information on CLC Bioinformatics Database, go to:
www.clcbio.com/database

About CLC bio

CLC bio is the world’s leading full-service bioinformatics solution provider, solely focusing on the development of bioinformatics: software, hardware, data analysis, and custom-designed bioinformatics algorithms. CLC bio is an Apple solution provider and value added reseller.

CLC bio’s mission is to be among the most innovative bioinformatics companies in the 21st century. This is realized through:

• Development of bioinformatics software and hardware based on the latest scientific findings
• User-friendly, integrated and intuitive cross-platform software solutions
• Continuous focus on customer needs and superior customer service
• Frequent product updates including the latest IT technologies and bioinformatics algorithms
• A flexible IT architecture, enabling customers to buy or develop individualized solutions at a reasonable price