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Engineered molecules mark specific proteins inside...

Like mobsters following strict orders, newly engineered molecules called “ubiquibodies” can mark specific proteins inside a cell for destruction – a molecular kiss of death that is paving the way for new drug therapies and powerful research tools. Led by professor Matthew DeLisa, chemical engineers at Cornell University have developed a new type of antibody, called a “ubiquibody,” which is an...

B-cells aggravate autoimmune diseases

Scientists in Freiburg may have discovered a fundamental aggravating factor in autoimmune diseases. If B-lymphocytes lack the protein PTP1B, the cells will become hyperactive for stimulatory signals and can thus promote an autoimmune attack. This study offers an additional explanation to how B-cells regulate an immune response. In Germany, approximately 800,000 people suffer from rheumatoid arthritis. In this progressive...

Gel steers tooth tissue formation

A bit of pressure from a new shrinking, sponge-like gel is all it takes to turn transplanted unspecialized cells into cells that lay down minerals and begin to form teeth. The bioinspired gel material could one day help repair or replace damaged organs, such as teeth and bone, and possibly other organs as well, scientists from the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard School of...

Ancient mystery of cell division solved

An international team of scientists led by the University of Göttingen has deciphered a key mechanism of cell division. A striking feature of cell division is the condensation or compaction of chromosomes, which was first observed more than 130 years ago, but whose mechanism had been only vaguely understood so far. The Göttingen researchers successfully identified a force in a dividing cell that drives this process. The...

Mechanical forces at work in living cells and tiss...

Don Ingber, of Harvard University’s Wyss Institute for Biologically Inspired Engineering, is a mechanobiologist – a member of the small but growing community of scientists who look at biological systems through the lens of physics. Mechanobiologists hope to add to our understanding of physiology, embryology, and disease ontogeny by observing the mechanical forces at work in living cells and tissues. Ingber sees this work...

StemCyte and UC Davis Tethered in Umbilical Cord B...

StemCyte entered an agreement with the UC Davis Umbilical Cord Blood Collection (UCB) Program to advance the collection, processing, and registration of high quality and diverse cord blood cells from California mothers for public banking. According to the company, the agreement is the first of its kind under California’s statewide program. Legislation signed into law in 2010 called for the University of California to...
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