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Trana Discovery and Southern Research Institute Fi...

Trana Discovery and Southern Research Institute Find Bioactive HIV Antiviral Compounds: NIAID contracts additional $700,000 to screen 300,000 more compounds for HIV inhibition PRNewswire – October 28, 2009 CARY, N.C. and BIRMINGHAM, Ala., Oct. 28 /PRNewswire-USNewswire/ — Trana Discovery, Inc., an infectious disease drug discovery technology company, and Southern Research Institute, a not-for-profit contract...

Researchers find candidates for new HIV drugs

While studying an HIV protein that plays an essential role in AIDS progression, researchers at the University of Pittsburgh School of Medicine have discovered compounds that show promise as novel treatments for the disease. HIV drug discovery efforts have met with little success in finding compounds that interact with an important HIV virulence factor, called Nef, because it lacks biochemical activity that can be directly...

Progress in Finding a New Class of HIV Drugs

Scientists have discovered a method for screening an entirely new class of drugs, targeted against the HIV protein Nef, according to an article published online October 6 in ACS Chemical Biology and reported by ScienceDaily. HIV’s Nef protein has an important indirect influence on how well HIV functions in the body. The presence of Nef inhibits HIV-infected cells from signaling to other cells that they are infected....

AIDS Study Flushes Out Hidden Virus, Pointing to P...

Oct. 2 (Bloomberg) — Scientists, moving closer to a cure for AIDS, identified a way to find medicines that would help rid patients of the hardest-to-treat pockets of HIV. Current anti-HIV drugs reduce the virus to undetectable levels without eradicating it. The virus survives by lying dormant in immune-system cells, where the medicines don’t reach them. Scientists from Johns Hopkins University and the Howard...

Virtual Screening Gives Drug Design a Boost

San Diego, CA (OBBeC) – Researchers at the University of California, San Diego, developed a unique computational approach to identify key compounds that could lead to new drugs to combat African sleeping sickness — a disease spread by the biting tsetse fly and caused by the parasite Trypanosoma brucei. Around 150,000 people per year get African sleeping sickness. Unless treated, the illness is invariably fatal...

Seegene/Lab901 brings a New Detection Platform for...

Rockville, MD, and Edinburgh, Scotland, June 17, 2008:  Seegene and Lab901 today announced the availability of a novel automated multi-pathogen walk-away detection platform for European hospitals. Based on the Seeplex(R) multiplexing PCR system and ScreenTape(R)  gel electrophoresis detection system, this new Seeplex/ScreenTape detection platform will be introduced to clinical and research laboratories in 10...
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