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Stroke drug shows promise for people with Lou Gehr...

Keck School of Medicine of USC neuroscientists have unlocked a piece of the puzzle in the fight against Lou Gehrig’s disease, a debilitating neurological disorder that robs people of their motor skills. Their findings appear in the online edition of the Proceedings of the National Academy of Sciences of the United States of America, the official scientific journal of the U.S. National Academy of Sciences. “We know...

Caffeine-based compound targets tau deposits in Al...

German and French researchers have found a key clue in how caffeine may work to protect the brain against the devastating effects of Alzheimer’s disease. In a two-year study, investigators from the University of Bonn and the University of Lille found that caffeine has a positive effect on tau deposits–clumps of tau proteins that form neurofibrillary tangles, causing disruptions in nerve cell communication and...

Antioxidant could slow progression of Lou Gehrig&#...

An antioxidant discovered more than a dozen years ago may some day be able to treat patients with amyotrophic lateral sclerosis, a devastating neurodegenerative disease that is usually fatal within 5 years of diagnosis and currently has no cure. Researchers at the Universidad de la Republica in Uruguay found that the antioxidant MitoQ prolonged the lifespan and improved the health of mice suffering from an animal form of ALS,...

Prion discovery helps keep deadly brain diseases i...

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, PhD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that may help keep deadly neurological diseases in check for months or years. The findings, published in The Journal of Clinical Investigation, “present a breakthrough in understanding the secret life of prion molecules in the...

Parkinson’s as an autoimmune disease

Parkinson’s disease, like Alzheimer’s disease, is one of the leading neurodegenerative issues being targeted by the biopharmaceutical and life sciences industries today. It is the result of the death of neurons responsible for producing dopamine, which the Parkinson’s Disease Foundation describes as “A chemical messenger that regulates movement by assisting in the effective communication (transmission) of...

Experimental supplement extends lifespan, stops me...

A drug supplement that activates a protein involved in metabolic balance showed an extension in lifespan and improvement in the overall health of mice, according to a new study.The findings, published Feb. 27 in Cell Reports, may eventually help scientists develop therapies to minimize the effects of age-related metabolic and chronic diseases on the human body. Researchers, led by Dr. Rafael de Cabo of the National Institute...
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