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Imaging technique captures the vibrations of prote...

Like the strings on a violin or the pipes of an organ, the proteins in the human body vibrate in different patterns, scientists have long suspected. Now, a new study provides what researchers say is the first conclusive evidence that this is true. Using a technique they developed based on terahertz near-field microscopy, scientists from the University at Buffalo and Hauptman-Woodward Medical Research Institute (HWI) have for...

Potential drug targets for early onset glaucoma

Using a novel high-throughput screening process, scientists have for the first time identified molecules with the potential to block the accumulation of a toxic eye protein that can lead to early onset of glaucoma. Glaucoma is a group of diseases that can damage the eye’s optic nerve and cause vision loss and blindness. Elevated eye pressure is the main risk factor for optic nerve damage. Researchers have implicated a...

Key hep C protein revealed

In a discovery that could put a vaccine for hepatitis C closer in sight, researchers have been able to characterize a key protein in the virus that aids infection in the liver. The structure of the protein, known as E2 envelope glycoprotein, has up until now evaded scientists. But the new, detailed picture of the protein obtained by investigators at The Scripps Research Institute in La Jolla, CA, is an important development...

Software Mines Science Papers

Software that read tens of thousands of research papers and then predicted new discoveries about the workings of a protein that’s key to cancer could herald a faster approach to developing new drugs. The software, developed in a collaboration between IBM and Baylor College of Medicine, was set loose on more than 60,000 research papers that focused on p53, a protein involved in cell growth, which is implicated in most...

Phosphorylation: over 140 phosphospecific antibodi...

Phosphorylation plays critical roles in the regulation of many cellular processes. It is tightly associated with protein activity and is a key point of protein function regulation. Phosphorylation is the attachment of a phosphate group to a protein or other organic molecule. Once the new phosphate group is added by protein phosphorylation, it changes the structure of its host protein. The new phosphorus group alters the role...

Company and People Notes: Patheon and Solvias Form...

Nov 20, 2008 ePT–the Electronic Newsletter of Pharmaceutical Technology Company Notes San Jose, CA (Nov. 14)—AnaSpec established a new facility dedicated to peptide production that complies with good manufacturing practice (GMP). The new facility is adjacent to AnaSpec’s headquarters and provides 5000 ft2 of dedicated GMP space, including two Class 10,000 cleanrooms. AnaSpec produces GMP peptides...
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